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MSIF Arabic-language website goes "live"

MSIF is delighted to launch the first of a new series of language sections of the World of MS website. Each new section is a translation of core content of the English version of the website.

The translation includes basic information about symptoms, diagnosis and treatments of MS as well as MS society contact details and other useful resources in each language. Please click here to go to the new "live" Arabic site.

Last chance to take part in our caregiving survey!

Please take the opportunity to participate in our surveys about caregiving and MS - available online until Friday 27 October.

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New leader for MSIF's CEO Advisory Group

Peter Kauffeldt, CEO of the Danish MS Society, succeeds Alistair Fraser, retiring Chairman of MSIF's CEO Advisory Group.

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Profile of the Month : January 2008

Mohammad Tabiee

Country: Thailand
Age: 34
Year of diagnosis: 1998
Occupation: Quality Control Manager

English Spanish Italian German French Russian

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Sex ratio of multiple sclerosis in Canada: a longitudinal study

This Canadian study found that over the last 50 years a greater proportion of females than males have been developing MS and hypothesize that this is due to environmental factors, which if identified, could be addressed.

authors: Orton SM, Herrera BM, Yee IM, Valdar W, Ramagopalan SV, Sadovnick AD, Ebers GC; for the Canadian Collaborative Study Group.

source: Lancet Neurol. 2006 Nov;5(11):932-6.

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Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study

This study found that autoimmune diseases commonly run in families of people with MS, suggesting a general susceptibility to this type of disease, and that in families where this was the case, there was a link with the CTLA4 gene.

authors: Barcellos LF, Kamdar BB, Ramsay PP, Deloa C, Lincoln RR, Caillier S, Schmidt S, Haines JL, Pericak-Vance MA, Oksenberg JR, Hauser SL.

source: Lancet Neurol. 2006 Nov;5(11):924-31.

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Novel Olig 1-coding variants and susceptibility to multiple sclerosis

The authors identified new variants in the Olig1 gene, involved in remyelination after injury, but found no evidence to support the hypothesis that genetic variation in Olig1 influences susceptibility to multiple sclerosis.

authors: Goris A, Yeo TW, Maranian M, Walton A, Ban M, Gray J, Compston A, Sawcer S.

source: J Neurol Neurosurg Psychiatry. 2006 Nov;77(11):1296-7. Epub 2006 Jul 4.

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Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis

The authors found altered expression of neurofascin, a molecule involved in normal fast nerve conduction, in the brains of people with MS in areas of demyelination. This enhances our understanding of the underlying pathological processes.

authors: Howell OW, Palser A, Polito A, Melrose S, Zonta B, Scheiermann C, Vora AJ, Brophy PJ, Reynolds R.

source: Brain. 2006 Oct 14; [Epub ahead of print]

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Future-directed thinking and depression in relapsing-remitting multiple sclerosis

This study found some evidence to support the hypothesis that increased psychological well-being is associated with an ability to maintain aspects of the self which were not associated with the disease state.

authors: Moore AC, Macleod AK, Barnes D, Langdon DW.

source: Br J Health Psychol. 2006 Nov;11(Pt 4):663-75.

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Evaluation of a MS Specialist Nurse Programme

This questionnaire study assesses the impact of specialist MS nurses on various domains of health care for people with MS.

authors: Forbes A, While A, Mathes L, Griffiths P.

source: Int J Nurs Stud. 2006 Nov;43(8):985-1000. Epub 2006 Jan 18.

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ACTRIMS meeting focuses on search for biomarkers in MS

source: US National MS Society

Researchers have long wished for a simple blood test or other tool to diagnose and track the course of MS, or to detect the effectiveness of therapies. The search for this kind of easily detectable signal, or “biomarker,” is heating up, as evidenced by presentations at the 11th annual meeting of ACTRIMS (Americas Committee for Treatment and Research in Multiple Sclerosis), held on 8 October, 2006 in Chicago, USA.

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Australian MS website for children

source: Multiple Sclerosis Australia

Australia's Multiple Sclerosis Society of Queensland, with the support of Newman’s Own Foundation, has announced that "MS Info 4 Kids" is now on the web. The website answers questions that children with a parent with MS may have.

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New study: how B cells may contribute to damage of nerve fibers in MS

source: US National MS Society

Multiple sclerosis is generally thought to be launched by the immune cells known as T cells, but evidence is growing on the role of immune B cells in the attack on the brain and spinal cord.

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Supermodel Alessandra Ambrosio named US National Multiple Sclerosis Society Ambassador

source: US National MS Society

Supermodel Alessandra Ambrosio has accepted the role of a National Ambassador for the US National Multiple Sclerosis Society. Alessandra is known as a Victoria Secret contract Angel and is one of the most recognised models in North America today.

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US FDA expands approval of Betaseron® to include those at high risk for developing MS

source: US National MS Society

Berlex, Inc. (the US affiliate of Schering AG) have announced that the US Food and Drug Administration (FDA) has approved expanding the indication of Betaseron® (interferon beta-1b, Berlex, Inc.) to include patients at high risk for MS.

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