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MSIF awards six 2007 Du Pré Grants to young MS researchers

MSIF is delighted to announce that six young MS researchers have been awarded Du Pré Grants to allow them to study in another country.

The successful candidates are from, and travelling to, a range of countries to undertake varied MS research projects for between 10 weeks and one year. The aim is to encourage cross-fertilisation of skills through collaborative research projects.

Read more about the successful candidates

Interactive MSIF Board and Committee meetings set scene for Council 2007

Between 18-20 April MSIF held its Spring 2007 Board and Committee meetings in London for 40 delegates from around the world.

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Profile of the Month : January 2008

Erlend Berntsen

Age: 27
Country: Norway
Occupation: Admissions Officer
Year of diagnosis: 2000

"I’ve tried to maintain my hopes and dreams for the future."

English Italiano Espanol Deutsch Francais Russian

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Natalizumab treatment for multiple sclerosis: recommendations for patient selection and monitoring

In this important paper the authors review the current information on Natalizumab, a new preventive treatment for MS, including selection criteria for eligibility and recommended monitoring assessments.

authors: Kappos L, Bates D, Hartung HP, Havrdova E, Miller D, Polman CH, Ravnborg M, Hauser SL, Rudick RA, Weiner HL, O'connor PW, King J, Radue EW, Yousry T, Major EO, Clifford DB.

source: Lancet Neurol. 2007 May;6(5):431-41.

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An exploratory study on interferon beta dose effect in reducing size of enhancing lesions in multiple sclerosis

The authors focused on the effect of different dosages of Interferon-beta in reducing the size of active lesions on MRI. They found that only higher dosages reduce active lesions’ dimensions over time.

source: Mult Scler. 2007 May;13(3):343-7.

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Predicting beta-interferon failure in relapsing-remitting multiple sclerosis

The authors looked at which clinical parameters predict a poor response to Interferon-beta and found that a high degree of disability at the beginning of treatment and incomplete relapse suppression during treatment were predictive.

authors: O'rourke K, Walsh C, Antonelli G, Hutchinson M.

source: Mult Scler. 2007 May;13(3):336-42

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Treatment of pediatric multiple sclerosis and variants

The authors review the current knowledge regarding available treatments for MS in children, including both preventive and symptomatic medications.

authors: Pohl D, Waubant E, Banwell B, Chabas D, Chitnis T, Weinstock-Guttman B, Tenembaum S.

source: Neurology. 2007 Apr 17;68(16 Suppl 2):S54-65

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Natalizumab reduces visual loss in patients with relapsing multiple sclerosis

The authors looked at the effects of treatment with Natalizumab, a new treatment for MS, on visual acuity. They found that it was effective in reducing visual loss in people with relapsing MS.

authors: Balcer LJ, Galetta SL, Calabresi PA, Confavreux C, Giovannoni G, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Miller DH, O'Connor PW, Phillips JT, Polman CH, Radue EW, Rudick RA, Stuart WH, Wajgt A, Weinstock-Guttman B, Wynn DR, Lynn F, Panzara MA.

source: Neurology. 2007 Apr 17;68(16):1299-304.

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Clinical features of children and adolescents with multiple sclerosis

The authors summarised the clinical features of MS particular to children and compared them with clinical characteristics of MS in adults.

authors: Ness JM, Chabas D, Sadovnick AD, Pohl D, Banwell B, Weinstock-Guttman B.

source: Neurology. 2007 Apr 17;68(16 Suppl 2):S37-45.

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The psychosocial consequences of pediatric multiple sclerosis

The authors review the psychological impact of MS in children. They highlight the importance of a proper assessment and intervention on both emotional and cognitive problems.

authors: Macallister WS, Boyd JR, Holland NJ, Milazzo MC, Krupp LB.

source: Neurology. 2007 Apr 17;68(16 Suppl 2):S66-9.

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Health-related quality of life in secondary progressive multiple sclerosis

The authors studied the impact of different symptoms on the quality of life reported by patients with secondary progressive MS. They found that disability and fatigue negatively influence the wellbeing of these patients.

authors: Beiske AG, Naess H, Aarseth JH, Andersen O, Elovaara I, Farkkila M, Hansen HJ, Mellgren SI, Sandberg-Wollheim M, Sorensen PS, Myhr KM.

source: Mult Scler. 2007 May;13(3):386-92

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Analysis shows Tysabri helps reduce vision loss in relapsing MS

source: US National MS Society

In the first large-scale validation of a new method for evaluating visual function in multiple sclerosis, analysis of data from two pivotal clinical trials of Tysabri® showed that the drug can reduce vision loss in relapsing multiple sclerosis.

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Results of quality of life research in Spain published

source: FELEM

The Spanish MS Society FELEM have published the findings of a two year quality of life research project.

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Landmark compendium on paediatric MS published with funding from the US National MS Society

source: US National MS Society

The journal Neurology has published a comprehensive supplement on paediatric multiple sclerosis, the first publication of its kind, funded by the US National MS Society and written by the International Pediatric MS Study Group.

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US society-funded researchers find cells that may promote myelin repair in MS

source: US National MS Society

Researchers funded in part by the US National MS Society’s Promise:2010 campaign report on a potential source of cells in the brain to promote repair of nervous system damage that occurs in multiple sclerosis.

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