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Pain edition of MS in focus now available in Spanish and German

Issue 10 looks at pain and MS and includes information about why pain occurs in MS, the most common types of pain experienced, how pain can impact the lives of people with MS and some of the current treatment options available.

A special thank you to Pablo Villoslada (University of Navarra, Spain) for checking the Spanish edition and Gabriele Seestaedt (German MS Society - DMSG) for checking the German edition. For a free download please click here: Spanish German English

Free printed English copies and a commemorative folder which can hold all ten editions published so far can be ordered by request from info@msif.org.

Take part in our survey on stem cells

Help inform the next edition of MS in focus magazine by taking part in our short survey on stem cell research.

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Multiple Sclerosis Coalition endorses MSIF’s Quality of Life Principles

MSIF is delighted to announce that the US-based Multiple Sclerosis Coalition recently endorsed MSIF’s Principles to Promote the Quality of Life of People with MS (QoL Principles).

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Prague07 - register now

Prague07 - Living with MS: Today and Tomorrow will take place on 10 October 2007 (prior to ECTRIMS) at the Prague Congress Centre, Czech Republic.

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Profile of the Month : January 2008

Sophie Froger

Age: 50
Country: France
Occupation: Former attorney
Year of diagnosis: 2000

"Each day can bring us a few tiny moments of intense happiness."

English Espanol Deutsch Russian

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Spinal cord spectroscopy and diffusion-based tractography to assess acute disability in multiple sclerosis

The authors, using two recently introduced MRI techniques, evaluated spinal cord lesions during acute relapses in people with MS. They found that these measures help to clarify the underlying pathology of the spinal cord and correlate with acute disability.

authors: Ciccarelli O, Wheeler-Kingshott CA, McLean MA, Cercignani M, Wimpey K, Miller DH, Thompson AJ.

source: Brain. 2007 Aug;130(Pt 8):2220-31

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High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord

The authors, using a new MRI technique, looked at spinal cord lesions of rats affected by the animal form of MS. They found that this technique was very effective in detecting neuronal damage distant from inflammation sites.

authors: DeBoy CA, Zhang J, Dike S, Shats I, Jones M, Reich DS, Mori S, Nguyen T, Rothstein B, Miller RH, Griffin JT, Kerr DA, Calabresi PA.

source: Brain. 2007 Aug;130(Pt 8):2199-210.

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The involvement of mitochondria in the pathogenesis of multiple sclerosis

The authors reviewed the role of mitochondria, little cell components aimed at producing energy, in different pathologic processes underlying MS, from inflammation to nerve degeneration.

authors: Kalman B, Laitinen K, Komoly S.

source: J Neuroimmunol. 2007 Aug;188(1-2):1-12.

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Therapeutic use of dextromethorphan: Key learnings from treatment of pseudobulbar affect

The authors looked at the effect of a cough suppressant in reducing uncontrollable outbursts of laughing and crying in people with MS. They found it to be safe and effective in reducing this symptom.

authors: Miller A, Panitch H.

source: J Neurol Sci. 2007 Aug 15;259(1-2):67-73.

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US National MS Society research highlights

source: US National MS Society

The US National MS Society has recently made the Summer/Fall 2007 edition of Research Highlights, their newsletter of research progress, available on their website.

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Disappointing results for Beta Interferon

source: UK MS Society

Authors of an article published in this week's edition of The Lancet medical journal claim a recent study has shown that early treatment with beta interferon reduced the risk for progression of disability by 40 percent.

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Betaseron “BENEFIT” follow-up study results published

source: US National MS Society

In a study just published, researchers have shown for the first time that early treatment can slow the rate at which disability progresses in individuals who have had a first event suggestive of multiple sclerosis but who have not yet been diagnosed with definite MS.

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