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Three months until the Global Dinner Party 2008

With just over three months to go, begin planning your Global Dinner Party as soon as you can!

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Profile of the Month : January 2008

Name:
Allen O'Connor
Country: Ireland
Age: 58
Profession: Retired banker
Type of MS: RRMS
Year of diagnosis: 1985

...It is up to each of us to lead the life of our choice...

English Italian Russian German Spanish French

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Myelin repair: the role of stem and precursor cells in multiple sclerosis

Stem cell research is a new and exciting area, which is currently under ongoing development. The authors review recent progress explaining how stem cells may be able to help to repair myelin damage in MS.

authors: Chandran S, Hunt D, Joannides A, Zhao C, Compston A, Franklin RJ.

source: Philos Trans R Soc Lond B Biol Sci. 2008 Jan 29;363(1489):171-83.

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An investigation of the retinal nerve fibre layer in progressive multiple sclerosis using optical coherence tomography.

This study used OCT to look at the thickness of the retinal nerve fibres in the eye in people with progressive types of MS. They found that people with secondary, and to a lesser extent primary, progressive MS had a thinner nerve fibre layer reflecting loss of axons, which is the process thought to cause disability.

authors: Henderson AP, Trip SA, Schlottmann PG, Altmann DR, Garway-Heath DF, Plant GT, Miller DH.

source: Brain. 2007 Dec 4 [Epub ahead of print]

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Altered functional and structural connectivities in patients with MS: a 3-T study.

The authors combined two new MRI techniques to link structural damage in the motor pathways of people with MS to brain reorganization, thought to help limit disability.

authors: Rocca MA, Pagani E, Absinta M, Valsasina P, Falini A, Scotti G, Comi G, Filippi M.

source: Neurology. 2007 Dec 4;69(23):2136-45

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Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection.

The authors looked at which genes are expressed in the brain white matter in people with MS and found evidence that both inflammatory and anti-inflammatory genes are at work.

authors: Zeis T, Graumann U, Reynolds R, Schaeren-Wiemers N

source: Brain. 2007 Dec 4 [Epub ahead of print]

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Mitochondria in multiple sclerosis

The authors review the role of mitochondria, cellular constituents involved in energy production, in the pathogenesis of MS.

authors: Ghafourifar P, Mousavizadeh K, Parihar MS, Nazarewicz RR, Parihar A, Zenebe WJ.

source: Front Biosci. 2008 Jan 1;13:3116-26.

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Possible link between genes and types of MS

New research announced there may be an association between certain genes and the severity of MS.

The study compared genes taken from people with severe MS who used wheelchairs within five years of being diagnosed and people who had no discernable disability 20 years after diagnosis.

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Breaking down the barriers for employees with disabilities

3 December was International Day of Disabled Persons and the International Labor Organization (ILO) released a report, “The right to decent work of persons with disabilities”, detailing how new efforts are needed to break down the barriers that prevent millions of people with disabilities from working and contributing to the economic growth of their societies.

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