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MS in focus magazine on pain now available

Issue 10 of MS in focus is now available to read or download from our website.

This edition of the magazine looks at pain and MS and includes information about why pain occurs in MS, the most common types of pain experienced, how pain can impact the lives of people with MS and some of the current treatment options available. You can also read the personal experiences of people around the world who answered our online survey on pain, as well as an interview with Stephen Papadopoulos from Australia, who has pain as part of his MS.

To download this and earlier editions of the magazine for free or to read them online, please click here. Printed copies will be available shortly.

2007 Du Pré awards nominations deadline - 30 July 2007

MSIF is offering sponsorship opportunities for young MS researchers to work on projects in another country with the 2007 Du Pré Fellowship and the autumn 2007 Du Pré Grants. The deadline for nominations is 30 July 2007.

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Profile of the Month : January 2008

Wendy Temple

Age: 49
Country: Australia
Occupation: Teacher
Year of diagnosis: 2003

"That would be my advice to anyone who has MS – there is always tomorrow. If you can’t do it today, try again tomorrow."

English Italiano Espanol Deutsch Francais Russian

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Regional variations in the prevalence of multiple sclerosis in French farmers

The authors looked at the number of people with MS among French farmers. They concluded that France is among the countries of medium to high number of cases and confirmed the previously noted effect of latitude on prevalence.

authors: Vukusic S, Van Bockstael V, Gosselin S, Confavreux C.

source: J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):707-9.

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Early prediction of the long term evolution of multiple sclerosis: the Bayesian Risk Estimate for Multiple Sclerosis (BREMS) score.

The authors applied a recently developed clinical score to people with MS. They found it to be useful in predicting the risk of reaching a progressive phase during the course of the disease.

authors: Bergamaschi R, Quaglini S, Trojano M, Amato MP, Tavazzi E, Paolicelli D, Zipoli V, Romani A, Fuiani A, Portaccio E, Berzuini C, Montomoli C, Bastianello S, Cosi V.

source: J Neurol Neurosurg Psychiatry. 2007 Jul;78(7):757-9.

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Autoimmune disease in families with multiple sclerosis: a population-based study

In this large study, the authors studied the number of other common autoimmune diseases in people with MS and their families. They found them to be no more prevalent than in the general population. In addition, they found that woman knew more details about their family medical history than men.

authors: Ramagopalan SV, Dyment DA, Valdar W, Herrera BM, Criscuoli M, Yee IM, Sadovnick AD, Ebers GC; for the Canadian Collaborative Study Group.

source: Lancet Neurol. 2007 Jul;6(7):604-10

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Quantitative diffusion weighted imaging measures in patients with multiple sclerosis

The authors used a recently developed MRI technique to detect subtle damage in the brain tissues of people with MS, and found that this was linked with clinical measures of disability.

authors: Tavazzi E, Dwyer MG, Weinstock-Guttman B, Lema J, Bastianello S, Bergamaschi R, Cosi V, Benedict RH, Munschauer FE 3rd, Zivadinov R.

source: Neuroimage. 2007 Jul 1;36(3):746-54

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Natural history of multiple sclerosis with childhood onset

The authors studied the disease course in people with childhood onset MS. They found that these people take longer to reach the progressive stage of the disease and are slower to accumulate irreversible disability than those with adult onset.

authors: Renoux C, Vukusic S, Mikaeloff Y, Edan G, Clanet M, Dubois B, Debouverie M, Brochet B, Lebrun-Frenay C, Pelletier J, Moreau T, Lubetzki C, Vermersch P, Roullet E, Magy L, Tardieu M, Suissa S, Confavreux C; Adult Neurology Departments KIDMUS Study Group.

source: N Engl J Med. 2007 Jun 21;356(25):2603-13.

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MSIF research grant recipient reports on her experiences

2006 Du Pré Grant recipient, Gabrièle Piaton

"This training period allowed me to acquire new expertise in the tissue culture model of central nervous system (CNS) myelination. I have also gained a better overview of the complex relationships affecting oligodendrocyte (OL) cell biology, which are involved in remyelination - an understanding of which could be relevant in the development of new therapeutic strategies promoting remyelination in disorders such as MS." Gabrièle Piaton

To read more about Gabrièle's research, please scroll down to the bottom of this link: 2006 Du Pré Grant Recipients

Further information on Du Pré funding opportunities can be found here. If you have any questions or queries please contact Zoe Burr.

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First UK map of MS specialists available for GPs

source: UK MS Trust

An interactive map to enable GPs to quickly locate specialist multiple sclerosis centres and specialist neurology teams throughout the UK has been created by the MS Trust and the UK MS Society.

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ACTRIMS and CMSC meetings focus on emerging MS therapies and quality of life issues

source: US National MS Society

The exciting world of “Emerging Therapies for Multiple Sclerosis” was the topic of the 12th annual meeting of ACTRIMS (Americas Committee for Treatment and Research in Multiple Sclerosis) on 2 June in Washington DC. For the first time, ACTRIMS was held in conjunction with the Consortium of MS Centers Annual Meeting.

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Multiple Sclerosis – Information Dividend (MS-ID) project to be co-funded by the European Commission with half a million Euro

source: EMSP

EMSP and its six MS-ID project partners are delighted to receive funding from the European Commission for this important information gathering project.

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Latin American Association for MS launches chat room and blog on website

source: ULASEM

The Asociación Latinoamericana para Esclerosis Múltiple/Latin American Association for MS Inc (ULASEM), in furthering their aim to unite people with MS in the region, have recently launched a chat room and blog on their website.

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Fampridine-SR study enroling US and Canadian patients with MS

source: US National MS Society

Investigators at approximately 35 centers in the United States and Canada are enroling participants in a 14-week clinical trial testing the safety and effectiveness of Fampridine-SR (an oral, sustained-release formula of 4-aminopyridine being developed by Acorda Therapeutics) compared with inactive placebo to improve walking ability in 200 people with all types of multiple sclerosis.

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