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Profile of the Month : January 2008

Name:
Ninfa Monarres Madrid
Country: Mexico
Age: 48
Profession: Childcare worker
Type of MS: RRMS
Year of diagnosis: 1999

'...I loved my job and was promoted to director, when I received an unexpected visit from MS, a friend I share with people all over the world: in Mexico alone there are 15,000 people with MS...'

Italiano Deutsche English Espanol Francais

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Neurogenesis and neuroprotection in the CNS - fundamental elements in the effect of glatiramer acetate on treatment of autoimmune neurological disorders.

This review focuses on the role of Glatiramer acetate (Copaxone) in encouraging the production of new nerve cells, as well as its effects on the immune system and its role in protecting the nerve against damage

authors: Arnon R, Aharoni R.

source: Mol Neurobiol. 2007 Dec;36(3):245-53. Epub 2007 Oct 11

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Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor.

This study in MS patients suggests that people with a specific genetic subtype are relatively protected . Those with the BDNF Met 66 allele, a single nucleotide polymorphism, appeared to have larger brain volumes and lower lesion loads.

authors: Zivadinov R, Weinstock-Guttman B, Benedict R, Tamaño-Blanco M, Hussein S, Abdelrahman N, Durfee J, Ramanathan M.

source: Hum Mol Genet. 2007 Nov 15;16(22):2659-68. Epub 2007 Jul 26

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The environment and the nervous system.

This review explores the interplay between genetic and environmental factors in causing MS. The author seeks to explain why studies so far have been inconclusive in identifying a specific causative viral agent in MS.

authors: Poser CM

source: J Neurol Sci. 2007 Nov 15;262(1-2):98-9. Epub 2007 Jul 25

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Cannabinoid control of neuroinflammation related to multiple sclerosis.

This review discusses the receptor-mediated immuno-modulatory effects of cannabinoids, which may not be evident at clinically safe doses. However, cannabinoids may have a role in neuroprotection via their effect on the innate immune system, in addition to a role in symptom control.

authors: Baker D, Jackson SJ, Pryce G.

source: Br J Pharmacol. 2007 Nov;152(5):649-54. Epub 2007 Sep 24.

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Scotland: Seeking answers with new MS Registry

source: BBC Scotland © BBC 2007

Scotland has the highest rate of MS in the world, with an estimated 10,500 people living with MS. Across the UK about one in every 800 people has MS, but in Scotland the figure is estimated at one in 500.

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UK: Funding for MS Life 2008

The UK MS Society is able to offer grants to individuals on a low income to assist with the cost of travel and accommodation. Priority will be given to individuals who live a long distance from Manchester.

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Canada: acne drug may help multiple sclerosis

Minocycline has been used as an acne treatment for over thirty years, and now its anti-inflammatory properties could be an important factor in fighting the symptoms of MS.

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Germany: 'History of MS' short film now available

The German MS Society (DMSG) has worked with MS researchers, including Professor Jürg Kesselring (Chefarzt Neurology Rehabilitation Centre Hospital Valens, Switzerland) and Professor Peter Rieckmann (Chair for MS Research, Director of the MS Program of the University of British Columbia and Vancouver Coastal Health, Canada) to create ‘Multiple Sclerosis - a journey through time’.

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Ecuador: Luncheon to celebrate National MS Day

On Sunday 11 November, to commemorate Ecuador’s National MS Day, the Fundación Ecuatoriana de Esclerosis Múltiple (FUNDEM) will host a 'Buffete Dominical' at their headquarters in Quito, Ecuador.

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Spain: Temas out now

Issue 16 of Spain’s Federación Española para la Lucha contra la Esclerosis Múltiple’s (FELEM) biannual magazine, Temas, is now available to download. This issue focuses on the effect on teenagers when a parent is diagnosed with MS.

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