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The 2007 McDonald Fellowship

We are delighted to announce that, further to our objective of stimulating MS research, we are awarding a record five McDonald Fellowships to allow five promising young MS researchers from Argentina, Brazil, Romania, Spain and Thailand to spend two years working in some of the world’s leading MS research centres.

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MS 2007 Global Bike Ride

Some of you may remember Scott McDermid, who was raising funds for MSIF and the Tyler Hamilton Foundation on the MS Global 2007 Bike Ride, run by the Tyler Hamilton Foundation. Scott raised over $8,000 for the fight against Multiple Sclerosis on the week-long cycling ride in the Italian Dolomites from 5-12 September.

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MSIF’s Prague07 page now live

Our Prague07 page, showing videos, presentations and photos from the Living with MS: Today and Tomorrow is now live.

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Sign the petition for the Ratification of the UN Convention on the Rights of Persons with Disabilities

If you haven't already, please sign MSIF's petition for the Ratification of the UN Convention on the Rights of Persons with Disabilities.

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Jaroslav Zika
Country: Czech Republic
Occupation: Retired Engineer
Year of diagnosis: 1987
Type of MS: PPMS

"I realise I lost my job and mobility to MS, but on the other hand I have learned things I would otherwise never have found out"

English Italian Russian German French Spanish Czech

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Regional brain atrophy development is related to specific aspects of clinical dysfunction in multiple sclerosis.

The authors looked at the relationship between the localization of brain atrophy and the degree of disability in specific tests in a group of MS patients. They found that lower limbs dysfunction was related with atrophy of central brain regions, whereas upper limbs dysfunction was related with atrophy of peripheral areas.

authors: Jasperse B, Vrenken H, Sanz-Arigita E, de Groot V, Smith SM, Polman CH, Barkhof F.

source: Neuroimage. 2007 Nov 15;38(3):529-37. Epub 2007 Aug 16

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Multiparametric magnetic resonance imaging analysis of the corticospinal tract in multiple sclerosis

The authors used different recently introduced MRI techniques to study the cortico-spinal tract, which is a group of fibres responsible for mobility, in a group of people with MS. They found that these techniques are very sensitive in detecting abnormalities in this brain region.

authors: Reich DS, Smith SA, Zackowski KM, Gordon-Lipkin EM, Jones CK, Farrell JA, Mori S, van Zijl PC, Calabresi PA.

source: Neuroimage. 2007 Nov 1;38(2):271-9. Epub 2007 Aug 15.

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Detecting treatment effects on brain atrophy in relapsing remitting multiple sclerosis: Sample size estimates.

This study investigates how many patients would need to be recruited to a clinical trial in order to demonstrate a statistically meaningful effect of treatment on brain volume in relapsing remitting MS.

authors: Anderson VM, Bartlett JW, Fox NC, Fisniku L, Miller DH.

source: J Neurol. 2007 Oct 25; [Epub ahead of print]

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Azathioprine for multiple sclerosis

This review looks at all the information available for the immuno-modulatory agent azathioprine in MS. The study concludes that evidence suggests that azathioprine is an appropriate MS treatment, though patients should be monitored for side effects.

authors: Casetta I, Iuliano G, Filippini G.

source: Cochrane Database Syst Rev. 2007 Oct 17;(4):CD003982.

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Argentina: EMA’s Halloween Tea Party

The Argentinian MS Society, EMA, is holding an EMA benefit at the British Embassy on Wednesday 31st October.

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