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Autumn 2008 Du Pré Grants deadline approaching

Every year, MSIF offers up to ten Du Pré Grants of between £1-5000 to young MS researchers to enable them to undertake short visits to other MS research centres, either to learn more from each other or to carry out parts of joint research projects. The aim is to encourage cross-fertilisation of skills through collaborative research projects.

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Profile of the Month : June 2008

Name: Christo Balabanov
Country: Bulgaria
Age: 49
Profession: Mechanical engineer
Type of MS: Secondary progressive
Year of diagnosis: 1991

"How Multiple Sclerosis changed my life
(What I gained and lost from MS)"

English Italiano Francais Espanol Russian Deutsche

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Functional cortical changes of the sensorimotor network are associated with clinical recovery in multiple sclerosis.

The authors used functional MRI to study changes in activation of the brain in areas related to movement in people with MS after an acute motor relapse. They found different patterns of activation of various areas depending upon whether patients were using their affected or unaffected hand.

authors: Mezzapesa DM, Rocca MA, Rodegher M, Comi G, Filippi M.

source: Hum Brain Mapp. 2008 May;29(5):562-73

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Recombinant interferon beta or glatiramer acetate for delaying conversion of the first demyelinating event to multiple sclerosis.

The objective of this review was to assess whether immunomodulatory drugs prevented conversion from clinical isolated syndrome to MS. Interferon-beta was shown to prevent a second attack after two years of follow-up. This is consistent with what we know about interferon preventing relapses. The authors recommend further analysis of which patient subgroups might benefit.

authors: Clerico M, Faggiano F, Palace J, Rice G, Tintorè M, Durelli L.

source: Cochrane Database Syst Rev. 2008 Apr 16;(2):CD005278

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Quantitative magnetic resonance spectroscopy in the entire human cervical spinal cord and beyond at 3T.

MR spectroscopy is an MRI technique which provides information about the biochemistry of the brain. Due to technical challenges spinal cord spectroscopy has rarely been used. In this study the authors proposed a way to solve these problems in order to assess the cord with this technique.

authors: Henning A, Schär M, Kollias SS, Boesiger P, Dydak U.

source: Magn Reson Med. 2008 Apr 17 [Epub ahead of print]

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Magnetic resonance imaging metrics and their correlation with clinical outcomes in multiple sclerosis: a review of the literature and future perspectives.

This paper gives an overview of MRI techniques and their relationship with pathology and clinical status in MS.

authors: Bar-Zohar D, Agosta F, Goldstaub D, Filippi M.

source: Mult Scler. 2008 Apr 18 [Epub ahead of print]

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Glatiramer acetate after induction therapy with mitoxantrone in relapsing multiple sclerosis.

In this study, initial short-term treatment with mitoxantrone followed by 12 months of daily glatiramer was compared with glatiramer alone in people with MS. The addition of mitoxantrone decreased Gd-enhanced lesions and the relapse rate, but not measures of disability. The authors suggested that this treatment could be an option in severe MS.

authors: Vollmer T, Panitch H, Bar-Or A, Dunn J, Freedman MS, Gazda SK, Campagnolo D, Deutsch F, Arnold DL.

source: Mult Scler. 2008 Apr 18 [Epub ahead of print]

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2008 GDP – GEMS 2008 Art Auction, Chennai, India

As part of the 2008 Global Dinner Party (GDP), the Multiple Sclerosis Society of India’s (MSSI) Chennai Chapter held the ‘GEMS 2008’ Art Auction. The event took place in the Hotel Park Sheraton Towers in Chennai and artists from the length and breadth of India contributed their work with 27 paintings being auctioned.

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