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MSIF at MS Life

MSIF were at the MS Life event in Manchester over the weekend, talking to people with MS, their families, friends and carers. The programme for the weekend was outstanding, with a wide range of exhibitors, daily lectures and talks, and a crèche so parents could walk around without distraction for a little while!

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Christo Balabanov
Country: Bulgaria
Age: 49
Profession: Mechanical engineer
Type of MS: Secondary progressive
Year of diagnosis: 1991

How Multiple Sclerosis changed my life
(What I gained and lost from MS)

English Italiano Francais Espanol Russian

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Lack of TIM-3 Immunoregulation in Multiple Sclerosis

The authors studied the immune cells in people with MS, focusing on the role played by a cell regulatory factor, named TIM-3. They found that TIM-3 regulation is altered in people with MS, and that treatment with glatiramer and interferon-beta are partially able to restore its function.

authors: Yang L, Anderson DE, Kuchroo J, Hafler DA.

source: J Immunol. 2008 Apr 1;180(7):4409-4414

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Integrating risk factors: HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis.

This study focused on the relationship between two risk factors associated with the development of MS, namely antibodies against Epstein-Barr virus and a specific genetic pattern. The authors found that the level of antibody was an independent risk factor for MS even after accounting for any association with genetic pattern, but when the two factors occurred together, the risk of developing MS increased further.

authors: De Jager PL, Simon KC, Munger KL, Rioux JD, Hafler DA, Ascherio A.

source: Neurology. 2008 Mar 25;70(13 Pt 2):1113-8. Epub 2008 Feb 13

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Evidence of thalamic gray matter loss in pediatric multiple sclerosis.

The authors, using a new imaging technique, studied grey matter involvement in children with MS. They found that, in contrast to the adult form, the only affected area of grey matter was the thalamus, a deep region of the brain. They thought that this damage could be a consequence of lesions occurring in the connecting white matter.

authors: Mesaros S, Rocca MA, Absinta M, Ghezzi A, Milani N, Moiola L, Veggiotti P, Comi G, Filippi M.

source: Neurology. 2008 Mar 25;70(13 Pt 2):1107-12

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A longitudinal study of variations in and predictors of fatigue in multiple sclerosis.

The authors examined the different factors that could influence levels of fatigue in people with MS over a period of two years. They found that depressive symptoms, not working and living with a partner were associated with development of increased levels of fatigue over time.

authors: Johansson S, Ytterberg C, Hillert J, Widén Holmqvist L, von Koch L.

source: J Neurol Neurosurg Psychiatry. 2008 Apr;79(4):454-7.

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US: NMSS Bike MS Ride 2008

Established as one ride in 1980 in Minnesota, the National MS Society’s (NMSS) Bike MS Rides are now the country's largest organised charity bicycling event series. In 2007, more than 100,000 cyclists participated in 100 rides throughout the United States, raising more than $77 million.

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Saudi Arabia: Saudi MS Forum meeting

An MS Awareness Meeting for people newly diagnosed with MS and their families is being held in the western region of Saudi Arabia.

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