Multiple Sclerosis International Federation 12 August 2008


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Making Connections

 

MSIF News

Summaries of new MSIF activities, events, projects, programmes, resources, publications and more.
MS in focus milestone

We are delighted that downloads of our free magazine have passed the one million mark, highlighting its continued popularity among professionals working in MS and people with MS around the world.

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Profile of the Month

Summaries of news, views and achievements from people with MS around the world.

Profile of the Month : September 2008

Jim Wolfgang

Jim Wolfgang Canadian PwMSI Committee memberCountry: Canada
Age: 75
Occupation: Retired Union Representative
Type of MS: Primary progressive
Year of diagnosis: 1976

I have seen many positive changes in the way governments at every level in Canada have responded to people with MS; however, we still have a long way to go.

Read the full article here:

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Research News

Summaries of all the latest research findings on MS selected by a team based at the Institute of Neurology, London.
Dose comparison trial of sustained-release fampridine in multiple sclerosis

In this preliminary multicenter placebo-controlled study, the experimental new oral treatment fampridine was tested in people with MS. Although it was safe, only minor clinical improvements were observed.

authors: Goodman AD, Brown TR, Cohen JA, Krupp LB, Schapiro R, Schwid SR, Cohen R, Marinucci LN, Blight AR; For the Fampridine MS-F202 Study Group.

source: Neurology. 2008 Jul 30.

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Prognostic factors after a first attack of inflammatory CNS demyelination in children

Children who have an episode of inflammation of the brain sometimes go on to develop MS, but not always. This study investigated which risk factors were important in predicting further episodes. They found that MRI appearances and the number of different areas of the nervous system involved were important. Some features which were previously thought to suggest a low likelihood of developing MS were not found to be good predictors in this study.

authors: Neuteboom RF, Boon M, Catsman Berrevoets CE, Vles JS, Gooskens RH, Stroink H, Vermeulen RJ, Rotteveel JJ, Ketelslegers IA, Peeters E, Poll-The BT, De Rijk-Van Andel JF, Verrips A, Hintzen RQ.

source: Neurology. 2008 Jul 30.

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Is in utero early-exposure to interferon beta a risk factor for pregnancy outcomes in multiple sclerosis?

In this small retrospective study the authors investigated the effect of interferon on children from mothers with MS who had accidentally taken it at the start of their pregnancy. They found that these children had slightly lower birth weights but did not report any other serious side effects.

authors: Patti F, Cavallaro T, Lo Fermo S, Nicoletti A, Cimino V, Vecchio R, Laisa P, Zarbo R, Zappia M.

source: J Neurol. 2008 Jul 28.

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Perivascular spaces - MRI marker of inflammatory activity in the brain?

The authors of this study found a relationship between small spaces surrounding blood vessels in the brain, which are normally present in all people, and inflammation of the brain that occurs in people with MS. This finding may help us to better understand these inflammatory processes.

authors: Wuerfel J, Haertle M, Waiczies H, Tysiak E, Bechmann I, Wernecke KD, Zipp F, Paul F.

source: Brain. 2008 Aug 1.

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Efficacy and safety of a hip flexion assist orthosis in ambulatory multiple sclerosis patients

In this uncontrolled trial a group of people with MS who had weakness in one leg were invited to use a device to stabilise the hip. Significant improvements in strength, pain and gait were observed over 12 weeks.

authors: Sutliff MH, Naft JM, Stough DK, Lee JC, Arrigain SS, Bethoux FA.

source: Arch Phys Med Rehabil. 2008 Aug;89(8):1611-7.

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No effect of preterm birth on the risk of multiple sclerosis: a population based study

The pathology of MS is complex and environmental factors play a role. In this population based study, the authors looked for any possible relationship between preterm birth and risk of developing MS. They found no relationship at all.

authors: Ramagopalan S, Valdar W, Dyment D, Deluca G, Orton SM, Yee I, Criscuoli M, Ebers G, Sadovnick D.

source: BMC Neurol. 2008 Aug 1;8(1):30.

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Immune modulation and increased neurotrophic factor production in multiple sclerosis patients treated with testosterone

In this small study the effect of testosterone in the immune system of men with MS was investigated. There were some changes in the immune cells and the authors suggested that further studies should be done.

authors: Gold SM, Chalifoux S, Giesser BS, Voskuhl RR.

source: J Neuroinflammation. 2008 Jul 31;5(1):32.

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MS News

Summaries of MS news from websites around the world.
Latin American photography auction to raise money for Argentinian MS Society

source: Esclerosis Múltiple Argentina

More than 100 photographers from 11 different countries in Latin America are taking part in the auction, the proceeds of which will be donated to Esclerosis Múltiple Argentina (EMA).

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Multiple Sclerosis International Federation
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