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World MS Day latest: more than 50 per cent of MSIF members sign up

Has your MS society signed up to participate in the first ever World MS Day on Wednesday 27 May 2009?

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Profile of the Month : January 2009

Henri Goethals

Country: Belgium
Age: 62
Type of MS: Progressive MS
Year of Diagnosis: 1979

My attitude towards the disease has evolved considerably. In the beginning, nothing was stable or predictable, and everything was frightening. Now that the disease has taken a quieter course, life has become easier.

Deutsch English Espanol Francais Italiano Русский

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Subtraction MR images in a multiple sclerosis multicenter clinical trial setting

The authors compared a new MRI technique to detect MS lesions with a conventional one and they found it had higher sensitivity.

authors: Moraal B, Meier DS, Poppe PA, Geurts JJ, Vrenken H, Jonker WM, Knol DL, van Schijndel RA, Pouwels PJ, Pohl C, Bauer L, Sandbrink R, Guttmann CR, Barkhof F

source: Radiology. 2008 Nov 26. [Epub ahead of print]

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MRI in the diagnosis of pediatric multiple sclerosis

MRI diagnostic criteria have not yet been adopted for MS in children. The authors looked for differences in MRI features of MS and other demyelinating diseases and proposed some modifications to the current criteria for adults.

authors: Callen DJ, Shroff MM, Branson HM, Lotze T, Li DK, Stephens D, Banwell BL

source: Neurology. 2008 Nov 26. [Epub ahead of print]

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Role of MRI in the differentiation of ADEM from MS in children

ADEM is a disease which can present in a similar way to a first attack of MS, particularly in children. This study showed some differences in the MRI patterns between them that may be useful to distinguish them.

authors: Callen DJ, Shroff MM, Branson HM, Li DK, Lotze T, Stephens D, Banwell BL

source: Neurology. 2008 Nov 26. [Epub ahead of print]

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The intrathecal, polyspecific antiviral immune response: specific for MS or a general marker of CNS autoimmunity?

The authors studied the spinal fluid of people with MS and another autoimmune disease and compared the immune response to some viruses. They found that this response was not a general marker of autoimmunity and might be specific to MS although further work is needed.

authors: Jarius S, Eichhorn P, Jacobi C, Wildemann B, Wick M, Voltz R

source: J Neurol Sci. 2008 Nov 26. [Epub ahead of print]

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Attentional lapses, emotional regulation and quality of life in multiple sclerosis

This study showed that the way that people manage their emotions and maintain attention may contribute to quality of life in MS.

authors: Phillips LH, Saldias A, McCarrey A, Henry JD, Scott C, Summers F, Whyte M

source: Br J Clin Psychol. 2008 Nov 26. [Epub ahead of print]

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Results of a phase IIa clinical trial of an anti-inflammatory molecule, chaperonin 10, in multiple sclerosis

This preliminary study showed that chaperonin 10, a new potential treatment for MS, was safe and did not cause serious side-effects, but further studies are required to assess its effect on symptoms.

authors: Broadley S, Vanags D, Williams B, Johnson B, Feeney D, Griffiths L, Shakib S, Brown G, Coulthard A, Mullins P, Kneebone C

source: Mult Scler. 2008 Nov 27. [Epub ahead of print]

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Increase in relapse rate during assisted reproduction technique in patients with multiple sclerosis

It has been shown that hormones may play a role in disease activity in women with MS. This study showed an increase in relapse rate in women who were treated with hormones for infertility.

authors: Hellwig K, Schimrigk S, Beste C, Muller T, Gold R

source: Eur Neurol. 2008 Nov 28;61(2):65-68. [Epub ahead of print]

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UK MS Society calls for law change on unproven stem cell trials

source: UK MS Society

Following the recent guidelines on unproven stem cell treatments by the International Society for Stem Cell Research (ISSCR), the UK MS Society is calling on the UK government to change the law on advertising medicines.

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Great strides moved MS research forward during 2008

source: National MS Society USA

Funding from the National MS Society USA has helped contribute to significant advances in both clinical and laboratory studies in MS.

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Results of comparative Spain-Argentina MS study released

source: La Federación Española para la Lucha contra la Esclerosis Múltiple (FELEM)

The results of "Multiple Sclerosis: reality, social needs and quality of life," a comparative study between Spain and Argentina have been released.

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Multiple sclerosis seen to be associated with headache

source: MS Trust UK

Patients with MS are more apt to suffer from headaches than the general population, results of an Italian study hint.

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