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2008 Evelyn Nicholson Award for International Caregiver

Nominations for the 2008 Evelyn Nicholson Award for International Caregiver are now open.

The Nicholson Award is a great opportunity to recognise the work of caregivers in the global fight against MS and we encourage all national MS societies to participate.

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2008 Global Dinner Party – focus on Canada

The MS Society of Canada has been part of the MS Global Dinner Party since its inception in 2003. Every year the Society co-ordinates a nationwide drive to encourage people to get together with friends, family or work colleagues and host an event. In 2007 the Society raised over CAN$51,000, setting a new fundraising record for the country.

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Profile of the Month : February 2008

Name: Maarten Wilbers
Country: The Netherlands
Age: 46
Profession: Programmer/website developer
Type of MS: RRMS
Year of diagnosis: 2001

'...I decided to concentrate on the things I could still do rather than on the things I couldn't."

English Italian Russian Spanish

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Longitudinal magnetic resonance spectroscopic imaging of primary progressive multiple sclerosis patients treated with glatiramer acetate: multicenter study.

This analysis of a subgroup of patients from the PROMiSe trial (Trial of glatiramer acetate therapy in primary progressive MS) who underwent spectroscopy imaging showed that there was no differences in metabolite concentrations in the brains of patients who were treated with glatiramer acetate and those that were not. This suggests that treated patients did not derive any protection from the drug.

authors: Sajja BR, Narayana PA, Wolinsky JS, Ahn CW; the PROMiSe Trial MRSI Group.

source: Mult Scler. 2008 Jan;14(1):73-80. Epub 2007 Sep 19.

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Cervical Spinal Cord Lesions in Multiple Sclerosis: T1-weighted Inversion-Recovery MR Imaging with Phase-Sensitive Reconstruction.

This study has identified that a specific MRI sequence (T1-weighted Inversion-Recovery) may have an advantage over two other commonly used sequences for detecting spinal cord lesions in MS.

authors: Poonawalla AH, Hou P, Nelson FA, Wolinsky JS, Narayana PA.

source: Radiology. 2008 Jan;246(1):258-264.

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Effect of exercise training on quality of life in multiple sclerosis: a meta-analysis.

This review consolidates previous research findings on the effect of exercise on quality of life in MS, and found that exercise was associated with a small improvement in quality of life.

authors: Motl RW, Gosney JL.

source: Mult Scler. 2008 Jan;14(1):129-35. Epub 2007 Sep 19.

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Longitudinal magnetic resonance spectroscopic imaging of primary progressive multiple sclerosis patients treated with glatiramer acetate: multicenter study.

This analysis of a subgroup of patients from the PROMiSe trial (Trial of glatiramer acetate therapy in primary progressive MS) who underwent spectroscopy imaging showed that there was no differences in metabolite concentrations in the brains of patients who were treated with glatiramer acetate and those that were not. This suggests that treated patients did not derive any protection from the drug.

authors: Sajja BR, Narayana PA, Wolinsky JS, Ahn CW; the PROMiSe Trial MRSI Group.

source: Mult Scler. 2008 Jan;14(1):73-80. Epub 2007 Sep 19.

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Cerebrospinal fluid brain specific proteins in relation to nitric oxide metabolites during relapse of multiple sclerosis.

This study measured bio-markers for glial activation and axonal damage (part of the inflammatory and degenerative processes in MS), and nitric oxide metabolites in the spinal fluid of 34 patients within 2 weeks of clinical relapse. They found an increase in nitric oxide metabolites which correlated with reduced clinical recovery, and with certain biomarkers. This suggests that nitric oxide metabolites may be partly responsible for sustained disability in MS.

authors: Rejdak K, Petzold A, Stelmasiak Z, Giovannoni G.

source: Mult Scler. 2008 Jan;14(1):59-66. Epub 2007 Sep 24.

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Mitoxantrone as induction treatment in aggressive relapsing remitting multiple sclerosis: treatment response factors in a 5 year follow-up observational study of 100 consecutive patients.

Of 100 patients with aggressive relapsing-remitting MS treated with mitoxantrone for six months, 78 were relapse free for one year, and reduction of relapses and disability was sustained over five years. Three patients developed asymptomatic cardiac dysfunction and one patient developed leukaemia which remitted with treatment.

authors: Le Page E, Leray E, Taurin G, Coustans M, Chaperon J, Morrissey SP, Edan G.

source: J Neurol Neurosurg Psychiatry. 2008 Jan;79(1):52-6. Epub 2007 Sep 10.

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Sophie Froger expedition DVD now available

Earlier this year we featured Sophie Froger, a French lady, who trekked across Canada raising awareness of MS.

Sophie has now released a DVD of her expedition, "Le Traîneau de l'Espoir" (Dogsled of Hope).

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UK MS Society members made MBEs

Alan Lindsley has been made MBE (Member of the British Empire) in the New Year Honours List, for his services to the Sunderland branch of the UK MS Society. The MBE is a British order of chivalry established in 1917 by King George V.

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