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Making Connections
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| Summaries of new MSIF activities, events, projects, programmes, resources, publications and more. |
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People with MS News
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| Summaries of news, views and achievements from people with MS around the world. |
Profile of the Month : February 2008
Name: Maarten Wilbers
Country: The Netherlands
Age: 46
Profession: Programmer/website developer
Type of MS: RRMS
Year of diagnosis: 2001
'...I decided to concentrate on the things I could still do rather than on the things I couldn't."
English Italian Russian Spanish
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Research News
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| Summaries of all the latest research findings on MS selected by a team based at the Institute of Neurology, London. |
Optic neuritis and multiple sclerosis
The author reviews the recent advances in the research about optic neuritis, one of the commonest initial symptoms in MS. A recently introduced technique, useful in quantifying the neuronal loss in the optic nerve following an episode of optic neuritis, is also discussed.
authors: Plant GT
source: Curr Opin Neurol. 2008 Feb;21(1):16-21
read more
Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: Preliminary comparative PET studies with [(11)C]vinpocetine and [(11)C]PK11195 in patients
The authors employed a new imaging technique in people with MS. They found that this technique is able to detect specific cells in the brain, named glial cells, and that it can be a marker of brain damage in MS.
authors: Vas A, Shchukin Y, Karrenbauer VD, Cselényi Z, Kostulas K, Hillert J, Savic I, Takano A, Halldin C, Gulyás B
source: J Neurol Sci. 2008 Jan 15;264(1-2):9-17
read more
Responsiveness and predictive value of EDSS and MSFC in primary progressive MS
The authors compared two widely used measures of disability in MS, the MSFC and the EDSS, in a group of patients affected by the primary progressive form of disease. Over two years they found the EDSS to be more responsive, although neither scale measured at baseline was very effective in predicting clinical deterioration over time.
authors: Kragt JJ, Thompson AJ, Montalban X, Tintoré M, Río J, Polman CH, Uitdehaag BM
source: Neurology. 2008 Jan 9
read more
Therapeutic vaccination with a trivalent T-cell receptor (TCR) peptide vaccine restores deficient FoxP3 expression and TCR recognition in subjects with multiple sclerosis.
The authors, using parts of abnormal immunological cells, developed a vaccine which could be potentially effective in people with MS. This preliminary study on 23 patients showed that therapeutic vaccination promoted a positive immunologic response, which was effective in counteracting the inflammatory reaction which characterizes the disease.
authors: Vandenbark AA, Culbertson NE, Bartholomew RM, Huan J, Agotsch M, LaTocha D, Yadav V, Mass M, Whitham R, Lovera J, Milano J, Theofan G, Chou YK, Offner H, Bourdette DN.
source: Immunology. 2008 Jan;123(1):66-78.
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MS News
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| Summaries of MS news from websites around the world. |
UK: MS Society Research Grant round 2008
The UK MS Society has announced two research grant rounds this year, in Autumn and Spring 2008. The research grants, totaling £5.6 million, support the aim for the highest standard of research in the MS field.
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Multiple Sclerosis International Federation
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