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2008 Global Dinner Party - Caitlin’s Story

My name is Caitlin, I am 11 years old and I have had MS since I was seven. Sometimes I get scared that I will lose my eyesight or get sick and not be able to walk and I will have to go to the hospital. I have to get a needle every second day that some times hurts but it helps me not get sick. Most times my life is pretty normal and I get to do normal things. I tell my story to other people because I HOPE they would like to donate for research so that we can find a cure and that no other kids or adults will have to spend their whole life with MS." Caitlin Kernaghan, Ontario, Canada

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Malta: MS Global Buffet Dinner Party

As the date for the 2008 MS Global Dinner Party approaches, participating national MS societies’ plans are now well underway.

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Spring 2008 Du Pré Grant deadline

The nomination deadline for the first round of the 2008 Du Pré Grants is fast approaching, with submissions needed by 15 February 2008.

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Profile of the Month : February 2008

Name: Maarten Wilbers
Country: The Netherlands
Age: 46
Profession: Programmer/website developer
Type of MS: RRMS
Year of diagnosis: 2001

'...I decided to concentrate on the things I could still do rather than on the things I couldn't."

English Italian Russian Spanish German

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The role of SVZ-derived neural precursors in demyelinating diseases: From animal models to multiple sclerosis

The authors review the role of stem cells, found in the brains of adults, in the process of myelin repair in animal models of multiple sclerosis, and in post-mortem studies in people. Preliminary studies suggest that these cells are activated in response to the disease process and contribute to the repair of demyelinated lesions. Further studies are needed to shed light on the nature of their action.

authors: Nait-Oumesmar B, Picard-Riéra N, Kerninon C, Baron-Van Evercooren A.

source: J Neurol Sci. 2008 Feb 15;265(1-2):26-31.

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Autologous mesenchymal bone marrow stem cells: Practical considerations

The authors explain the practical problems related to the auto-transplantation of stem cells from the bone marrow of people with MS. They conclude that this treatment is now considered safe enough to be tested in a pilot study in people.

authors: Scolding N, Marks D, Rice C.

source: J Neurol Sci. 2008 Feb 15;265(1-2):111-5.

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Epstein-Barr virus genotypes in multiple sclerosis

The authors studied whether infection with different types of Epstein-Barr virus, which may possibly be implicated in the development of MS, had a clear association with the disease, but they found none.

authors: Lindsey JW, Patel S, Zou J.

source: Acta Neurol Scand. 2008 Feb;117(2):141-4.

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Validation of linear cerebral atrophy markers in multiple sclerosis

The authors evaluated which MRI measures of enlargement of the ventricles of the brain were reliable metrics of brain volume loss in people with MS. They found that one of these measures was useful in monitoring brain volume loss over time.

authors: Butzkueven H, Kolbe SC, Jolley DJ, Brown JY, Cook MJ, van der Mei IA, Groom PS, Carey J, Eckholdt J, Rubio JP, Taylor BV, Mitchell PJ, Egan GF, Kilpatrick TJ.

source: J Clin Neurosci. 2008 Feb;15(2):130-7.

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A genome scan in a single pedigree with a high prevalence of multiple sclerosis.

In this genetic study, the authors looked at the genetic features of an unusual family in whom MS seems to be much more strongly inherited than usual. They found some specific genetic patterns involved in immune system control which might contribute to developing a predisposition to MS.

authors: Dyment DA, Cader MZ, Herrera BM, Ramagopalan SV, Orton SM, Chao M, Willer CJ, Sadovnick AD, Risch N, Ebers GC.

source: J Neurol Neurosurg Psychiatry. 2008 Feb;79(2):158-62.

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UK: MS Information Day for Asian community

The Asian MS Support Group is joining forces with the Confederation of Indian Organisations to hold an Asian MS Information Day, on Friday 25 January 2008.

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UK: Ministers to rethink Human Fertilisation and Embryology Bill

The Government will review consent laws that block cloning following a protest by leading scientists.

Ministers will re-assess two sections of the Human Fertilisation and Embryology Bill.

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