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MSIF's Quality of Life Principles available in Russian

MSIF's publication, the Principles to Promote the Quality of Life of People with Multiple Sclerosis is now available in Russian.

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Atlas of MS publication promotion work begins at MSIF

MSIF is working with the World Health Organization to produce the Atlas of MS. This major collaboration used a survey to determine the global epidemiology of MS and the resources to diagnose, inform, treat, rehabilitate, manage, support and provide services to people with MS in different countries.

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Profile of the Month : August 2008

Country: Argentina
Age: 37
Occupation: Social Communication Trainer, publicist, designer
Type of MS: Relapse remitting
Year of diagnosis: 2001

Throughout our lives, with or without MS, we face frustrating situations, disappointments and sadness, but we always find a way to keep going.

Read the full article here:

English Francais Espanol Italiano Deutsch Русский

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HLA-DRB1(*)15 allele influences the later course of relapsing remitting multiple sclerosis

The role of genes in the pathogenesis of MS is complex. The authors found an association between this gene and the development of secondary progressive MS, suggesting that it may be somehow involved.

authors: Cournu-Rebeix I, Génin E, Leray E, Babron MC, Cohen J, Gout C, Alizadeh M, Perdry H, Semana G, Brassat D, Clerget-Darpoux F, Yaouanq J, Edan G, Rosenheim M, Fontaine B.

source: Genes Immun. 2008 Jul 10. [Epub ahead of print]

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Brain responses to verbal stimuli among multiple sclerosis patients with pseudobulbar affect

The authors used a neurophysiological technique to study people with MS who had problems with emotional control. They found that people with problems with emotional control were more impulsive and that structures involved in sensory-motor and emotional processing seemed to be involved in this.

authors: Haiman G, Pratt H, Miller A.

source: J Neurol Sci. 2008 Aug 15;271(1-2):137-147. Epub 2008 May 27.

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Peripheral nerve demyelination in multiple sclerosis

MS characteristically affects the central nervous system. The authors looked for demyelination in the nerves outside the brain and spinal cord in people with MS and found it in 5 percent of them.

authors: Misawa S, Kuwabara S, Mori M, Hayakawa S, Sawai S, Hattori T.

source: Clin Neurophysiol. 2008 Aug;119(8):1829-33. Epub 2008 May 20.

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Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis

This article reviews the effects that different treatments for MS have on brain volume and the mechanisms of these changes.

authors: Zivadinov R, Reder AT, Filippi M, Minagar A, Stüve O, Lassmann H, Racke MK, Dwyer MG, Frohman EM, Khan O.

source: Neurology. 2008 Jul 8;71(2):136-44.

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Brain derived neurotrophic factor treatment reduces inflammation and apoptosis in experimental allergic encephalomyelitis

This study showed that this molecule was effective in reducing symptoms and central nervous system inflammation in the animal model of MS.

authors: Makar TK, Trisler D, Sura KT, Sultana S, Patel N, Bever CT.

source: J Neurol Sci. 2008 Jul 15;270(1-2):70-6. Epub 2008 Apr 18.

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New Venezuelan MS Association

source: Asociación Venezolana de Esclerosis Múltiple

The Asociación Venezolana de Esclerosis Múltiple (AVEDEM) was established on 8 July 2008 in Valencia, Venezuela.

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US: Researchers reprogramme adult stem cells in mouse brain to become myelin-making cells

source: US National MS Society

Researchers report that adult stem cells in mice that are on their way to becoming nerve cells can be redirected by changing a single gene to turn into cells that make nerve fiber-insulating myelin – the substance that is a key target of the immune attack in MS.

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UK: New publication about MS and the law

source: UK MS Society

The UK MS Society have produced a new publication about MS and the law.

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Spain: swimming fundraiser success

source: Federación Española Esclerosis Múltiple

The Federación Española Esclerosis Múltiple (FELEM) held Mójate 08 on 13 July 2008, with more than 92,000 people taking part.

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