7 April 2009

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MSIF News

Profile of the Month

Research News

MS News

Making Connections

MSIF News


	Summaries of new MSIF activities, events, projects, programmes, resources, publications and more.

World MS Day - have you registered yet?

Have you registered with the World MS Day website to show you are part of the global MS movement?

Fatigue edition of MS in focus now in Arabic!

We are delighted to launch our first edition of MS in focus in Arabic, and hope this will be a useful resource for Arabic-speaking people with MS around the globe.

MSIF supports the first International Pediatric Planning Symposium in Canada.

Initiated by the International Pediatric MS Study Group (IPMSSG), the first International Pediatric Planning Symposium took place in Toronto, Canada from 3 to 4 April 2009.

Profile of the Month


	Summaries of news, views and achievements from people with MS around the world.

Profile of the Month : January 2010

Mandi Kingsbury

Nationality: New Zealand
Age: 37
Profession: Fashion stylist and designer
Type of MS: Relapsing remitting
Year of diagnosis: 2003

I have no intention of slowing down or stopping my career. I protest my MS every day and I would like people to do the same in a positive way. You can’t predict what is going to happen with MS and I’d hate it to take away anything from my life.

Deutsch English Español Français Italiano

Research News


	Summaries of all the latest research findings on MS selected by a team based at the Institute of Neurology, London.

The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?

In this review Weiner reflects on the importance of understanding as best as possible the different pathogenic processes which take place in MS in order to find the best treatment, which should have an effect on the multiple involved pathways.

authors: Weiner HL

source: Ann Neurol. 2009 Mar 19;65(3):239-248

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

MS is characterised by demyelination of the central nervous system. Although in earlier stages a satisfactory recovery of this myelin loss may occur, in later stages this remyelinating process may fail, provoking persistent damage in the myelin and afterwards in the axon. The authors of this study have found an agent which is able to promote myelin regeneration both in vivo and in vitro. The findings of this study suggest that this new agent should be considered as a possible treatment for MS.

authors: Mi S, Miller RH, Tang W, Lee X, Hu B, Wu W, Zhang Y, Shields CB, Zhang Y, Miklasz S, Shea D, Mason J, Franklin RJ, Ji B, Shao Z, Chédotal A, Bernard F, Roulois A, Xu J, Jung V, Pepinsky B

source: Ann Neurol. 2009 Mar 18;65(3):304-315

Magnetic resonance imaging as a potential surrogate for relapses in multiple sclerosis: a meta-analytic approach

The aim of this work was to evaluate whether the treatment effects on magnetic resonance imaging (MRI) markers at the trial level were able to predict the treatment effects on relapse rate in relapsing-remitting multiple sclerosis.

authors: Sormani MP, Bonzano L, Roccatagliata L, Cutter GR, Mancardi GL, Bruzzi P

source: Ann Neurol. 2009 Mar 18;65(3):268-275

Pain and quality of life in the early stages after multiple sclerosis diagnosis: a 2-year longitudinal study

MS is a complex disease. From the clinical point of view, it can be extremely heterogeneous. When pain appears, the quality of life may be significantly reduced. This study shows that pain may occur in a high percentage of people with MS even at early stages of the disease. This finding suggests that pain should be carefully investigated and treated since the very beginning of the disease.

authors: Brochet B, Deloire MS, Ouallet JC, Salort E, Bonnet M, Jové J, Petry KG.

source: Clin J Pain. 2009 Mar-Apr;25(3):211-7

Prenatal and perinatal factors and risk of multiple sclerosis

The cause of MS is probably multifactorial and remains unknown. It had been suggested that prenatal and perinatal exposure to factors related to immunity could play a role in the development of MS in adulthood. The authors of this study aimed to investigate such immune-related prenatal or perinatal factors in a large group of people diagnosed with MS. Only modest correlations were found. The authors suggest that the results should be cautiously interpreted and stress the need of further studies to clarify the role that those prenatal and perinatal factors might actually play.

authors: Gardener H, Munger KL, Chitnis T, Michels KB, Spiegelman D, Ascherio A

source: Epidemiology. 2009 Mar 27

MS News


	Summaries of MS news from websites around the world.

World first: climbing Mount Everest with MS

source: Empowerment through Adventure

Lori Schneider from the USA hopes to be the first woman with MS to climb Mount Everest.

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