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Profile of the Month
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Making Connections
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| Summaries of new MSIF activities, events, projects, programmes, resources, publications and more. |
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Profile of the Month
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| Summaries of news, views and achievements from people with MS around the world. |
Profile of the Month : January 2010
Aida Alić
Country: Bosnia, living in Germany
Age: 32
Type of MS: Relapsing-remitting
Year of Diagnosis: 2000
"It was difficult to battle against people’s ignorance about MS, people said "well, if she has problems with her legs, she can work sitting down," and "I’ve heard MS is infectious."
 Deutsch English Español French Italiano Русский
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Research News
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| Summaries of all the latest research findings on MS selected by a team based at the Institute of Neurology, London. |
Do multimodal evoked potentials add information to MRI in clinically isolated syndromes?
People with MS may develop a certain degree of disability over time. However it is very difficult, after a first episode suggestive of MS, to identify the people who will have a faster accrual of disability. With this work, the authors suggest that carrying out complete neurophysiological tests, which investigate the integrity of the main pathways of the central nervous system, after a first episode of MS may help identify people with a higher risk of developing disability.
authors: Pelayo R, Montalban X, Minoves T, Moncho D, Rio J, Nos C, Tur C, Castillo J, Horga A, Comabella M, Perkal H, Rovira A, Tintore M
source: Mult Scler. 2009 Dec 7
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HLA-DRB1 and month of birth in multiple sclerosis
MS is a complex disease where both genetics and environment seem to play a role. The results of this study show an association between the month of birth, the presence of a specific genetic variant (associated with a higher risk of MS) and the risk of developing MS, suggesting a possible interaction of a seasonal risk factor with a genetic risk factor in the development of this disease.
authors: Ramagopalan SV, Link J, Byrnes JK, Dyment DA, Giovannoni G, Hintzen RQ, Sundqvist E, Kockum I, Smestad C, Lie BA, Harbo HF, Padyukov L, Alfredsson L, Olsson T, Sadovnick AD, Hillert J, Ebers GC
source: Neurology. 2009 Dec 15;73(24):2107-11
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Transplanted neural precursors enhance host brain-derived myelin regeneration
In MS, a chronic demyelinating disease of the central nervous system, the cells in charge of promoting the formation of new myelin in regions where myelin has been damaged fail to produce this remyelination. In this study the authors found that the transplantation of neural precursor cells, (cells that are due to become neural cells) into the brains of mice with the animal model of MS can facilitate remyelination in their brains.
authors: Einstein O, Friedman-Levi Y, Grigoriadis N, Ben-Hur T
source: J Neurosci. 2009 Dec 16;29(50):15694-
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Primary progressive multiple sclerosis diagnostic criteria: a reappraisal
Diagnosis of MS consists of the demonstration of dissemination in space and time of the characteristic demyelinating process occurring in the central nervous system. Current diagnostic criteria that consider dissemination in space for relapsing-remitting MS (RRMS) and primary progressive MS (PPMS) show significant differences. This means that the diagnostic process may become very difficult, especially for people suffering from PPMS. The results of this study suggest that the unification of the current criteria for dissemination in space for RRMS and PPMS should be seriously considered in future revisions of the diagnostic criteria for MS.
authors: Montalban X, Sastre-Garriga J, Filippi M, Khaleeli Z, Téllez N, Vellinga M, Tur C, Brochet B, Barkhof F, Rovaris M, Miller D, Polman Ch, Rovira A, Thompson A
source: Mult Scler. 2009 Dec;15(12):1459-65
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MS News
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| Summaries of MS news from websites around the world. |
Human rights: historic ratification by the European Union
source: European Disability Forum
On 26 November 2009 the European Community ratified the United Nations Convention on the Rights of Persons with Disabilities at a session of the Council of the European Union. This is an unprecedented step forward; it is the first human rights treaty ratified in the history of Europe and a great signal sent to all EU Members States.
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Presentations now available from EMSP information hour
source: European MS Platform
The European MS Platform (EMSP) held an information day, "More Quality of Life for MS Patients in Europe," on 9 December 2009, at the European Parliament in Brussels, Belgium. Presentations from this event are now available.
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Multiple Sclerosis International Federation
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