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MSIF News
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Profile of the Month
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MS News
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Making Connections
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| Summaries of new MSIF activities, events, projects, programmes, resources, publications and more. |
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Profile of the Month
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| Summaries of news, views and achievements from people with MS around the world. |
Profile of the Month : January 2010
Lori Schneider
Country: USA
Age: 52
Type of MS: rapidly progressing
Year of Diagnosis: 1999
"It was an amazing feeling to go step by step by step up Mount Everest with the World MS Day flag in my pack. Each step was hard and I had to concentrate on every aspect, and I had to really convince myself to keep going. It gave me a whole new feeling for people with MS who may have a hard time walking across a room. My difficulty on the mountain was short-lived, but I realised that some people with MS experience this level of difficulty with every step they take. I encourage them not to give up hope and to keep following their dreams!"
 Deutsch English Español French Italiano Русский
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Research News
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| Summaries of all the latest research findings on MS selected by a team based at the Institute of Neurology, London. |
Remyelination capacity of the MS brain decreases with disease chronicity
MS is an inflammatory-demyelinating disease of the central nervous system. It is known that demyelinated areas can recover the myelin by an internal repair mechanism of the damaged neural tissue by a process called remyelination. However, little is known about the characteristics of this protective process. The authors of this study aimed to investigate the frequency of remyelination in people with MS with different disease durations and the areas where this protective phenomenon was more prominent. They finally conclude that remyelination was more prominent in earlier stages of the disease and also that the location of the lesion may influence the extent of the remyelination.
authors: Goldschmidt T, Antel J, König FB, Brück W, Kuhlmann T
source: Neurology. 2009 Jun 2;72(22):1914-21
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Efficacy of intramuscular interferon beta-1a in patients with clinically isolated syndrome: analysis of subgroups based on new risk criteria
Some years ago interferon (IFN) beta was tested in people with a first episode suggestive of MS. It was proven to be effective in delaying the appearance of a second MS relapse. In the current study the authors have re-analysed the data from the former trial and have concluded that IFN beta was especially beneficial in delaying the second attack for those people whose first episode showed involvement of only one anatomical area. This finding reinforces the need for early disease modifying treatment after a first episode suggestive of MS, even when only mild anatomical involvement is observed.
authors: O'Connor P, Kinkel R, Kremenchutzky M
source: Mult Scler. 2009 Jun;15(6):728-34
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Twin studies and the heritability of MS: a conclusion
MS is a complex disease in which genes may play a role. In this study the authors aimed to investigate the relative contribution of genes and the environment to the appearance of MS by re-analysing six published studies from six countries, on people with MS who were twins. The authors found that the different methodologies and the huge variability in the results of the different studies prevented them from obtaining robust conclusions. They also suggested that further twin studies with improved methodology should be undertaken in people with MS, to more thoroughly investigate the genetic influence in the appearance of MS.
authors: Hawkes Ch, Macgregor A
source: Mult Scler. 2009 Jun;15(6):661-7
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MS News
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| Summaries of MS news from websites around the world. |
"Understanding MS" now available in Finnish
source: Deutsche Multiple Sklerose Gesellschaft Bundesverband
"Understanding MS," an online guide produced by the German MS Society, Deutsche Multiple Sklerose Gesellschaft Bundesverband (DMSG), is now available in three languages including Finnish.
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Multiple Sclerosis International Federation
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