Nitin J. Karandikar, MD, PhD (University of Texas Southwestern Medical Center, Dallas), a Harry Weaver Neuroscience Scholar of the National MS Society, and colleagues report their findings in the Journal of Immunology (2006 Jun 1;176(11):7119-29).

Copaxone is a synthetic compound made up of four amino acids (the building blocks of proteins) that are found in myelin. This drug is thought to stimulate one type of T cell (called a CD4+ T cell) in the body’s immune system to change from pro-inflammatory agents that attack the brain and spinal cord in MS, to beneficial agents that work to reduce inflammation at sites of damage in the nervous system.

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