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A six-week, placebo-controlled clinical trial of an oral spray drug derived from whole cannabis plants (Sativex®) involving 189 individuals with MS showed positive changes in a self-reported measurement of spasticity.
Spasticity is a common and often painful symptom of MS that involves feelings of stiffness, tightness or sudden movements caused by a wide range of involuntary muscle spasms. Those using the active drug were more likely to report subjective feelings of benefit versus those on inactive placebo, but other outcomes including the more objective Ashcroft Score for spasticity did not show statistically significant benefit.
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Source: US National MS Society
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