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According to the US Food and Drug Administration, there have been 13 confirmed cases of progressive multifocal leukoencephalopathy (PML, a viral infection of the brain that usually leads to death or severe disability) among people who have used Tysabri (natalizumab) after it became available for prescription in July 2006.
To read more, as reported by the US National MS Society, click here.
Source: US National MS Society
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