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summary: This study looked for evidence of subtle leakage of the barrier that separates the blood from the brain which is thought to be important in initiating inflammation in MS. It concluded that there was a detectable difference between white matter in non-enhancing lesions and normal appearing white matter. This leakage seemed not to be modified by the use of Natalizumab.
authors: Soon D, Altmann DR, Fernando KT, Giovannoni G, Barkhof F, Polman CH, O'connor P, Gray B, Panzara M, Miller DH.
source: J Neurol. 2007 Feb 3
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category: Imaging
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glossary:
ACE
Brain
Inflammation
Lesion
Multiple sclerosis
Physical
Placebo
Plaque
Relapsing/remitting MS
Sclerosis
White matter
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