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  B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: Implications for the lesion pathogenesis of multiple sclerosis.

summary: The authors investigated how a molecule which is involved in the immune system affects brain inflammation in mice. They found that the molecule contributed to reducing inflammation and therefore limiting damage.

authors: Ortler S, Leder C, Mittelbronn M, Zozulya AL, Knolle PA, Chen L, Kroner A, Wiendl H.

source: Eur J Immunol. 2008 Jun;38(6):1734-44.

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category: Immunology

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