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  Cladribine: an investigational immunomodulatory agent for multiple sclerosis

summary: This review looks at cladiribine, a new oral agent
that has been tried in relapsing-remitting and progressive MS. It has been shown to reduce enhancing lesions but the clinical significance of this is unclear and bone marrow suppression was a side effect. The authors conclude that more studies are needed.

authors: Brousil JA, Roberts RJ, Schlein AL.

source: Ann Pharmacother. 2006 Oct;40(10):1814-21. Epub 2006 Sep 19.

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category: Clinical Trials and Therapeutics

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glossary:

    Bone marrow
    Immunoglobulin
    Immunosuppressio
    Lesion
    Multiple sclerosis
    Plaque
    Relapsing/remitting MS
    Sclerosis
    Sign
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