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summary: Since the mechanisms of gray matter (GM) damage in MS are not yet fully understood, the authors of this study aimed to investigate the possible contribution of white matter (WM) lesions in harming the GM. The authors found that a higher volume of WM lesions in the visual pathway is associated with a greater loss of the connected GM, suggesting retrograde degeneration.
authors: Sepulcre J, Goñi J, Masdeu JC, Bejarano B, Vélez de Mendizábal N, Toledo JB, Villoslada P
source: Arch Neurol. 2009 Feb;66(2):173-9
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category: Imaging
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glossary:
Atrophy
Gene
Lesion
Multiple sclerosis
Plaque
Sclerosis
White matter
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