summary: Macrophages are cells that play a very important role in the body’s immune response. In this study, the authors looked at a molecule called SOCS1, whose role is to control the inflammation process, in an animal model of relapsing-remitting and chronic MS. They found that SOCS1 was present in greater quantity in the macrophages of animals with the relapsing-remitting form of disease, compared with those with the chronic form. They concluded that the presence of this molecule in macrophages may be important in determining the course of the disease.

authors: Berard JL, Kerr BJ, Johnson HM, David S.

source: Glia. 2010 Jul 19.

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category: Pathogens

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