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summary: In this multicentre study the authors aimed to assess the in vivo impact of neutralising antibodies on interferon beta (IFNb) bioactivity, by studying biomarkers of the IFNb response. Their findings suggest that high titers of neutralising antibodies abolish the in vivo response to interferon beta.
authors: Pachner AR, Warth JD, Pace A, Goelz S; INSIGHT investigators
source: Neurology. 2009 Nov 3;73(18):1493-500
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category: Clinical Trials and Therapeutics
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glossary:
Antibodies
Interferon
Neutralising
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