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  Effect of neutralizing antibodies on biomarker responses to interferon beta: the INSIGHT study

summary: In this multicentre study the authors aimed to assess the in vivo impact of neutralising antibodies on interferon beta (IFNb) bioactivity, by studying biomarkers of the IFNb response. Their findings suggest that high titers of neutralising antibodies abolish the in vivo response to interferon beta.

authors: Pachner AR, Warth JD, Pace A, Goelz S; INSIGHT investigators

source: Neurology. 2009 Nov 3;73(18):1493-500

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category: Clinical Trials and Therapeutics

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glossary:

    Antibodies
    Interferon
    Neutralising
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