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  Efficacy of treatment of MS with IFN{beta}-1b or glatiramer acetate by monthly brain MRI in the BECOME study

summary: In this randomised trial the efficacy of IFNb-1b (Betaferon/Betaseron®) and glatiramer acetate (GA, Copaxone®) were compared. Seventy-five people with RRMS were included in the study. After a 2-year treatment period the authors found no differences between the 2 groups in terms of MRI activity (new lesions and enhancing lesions) and clinical activity (new relapses).

authors: Cadavid D, Wolansky LJ, Skurnick J, Lincoln J, Cheriyan J, Szczepanowski K, Kamin SS, Pachner AR, Halper J, Cook SD

source: Neurology. 2009 Mar 11

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category: Clinical Trials and Therapeutics

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glossary:

    ACE
    Axon
    Brain
    Glatiramer
    Interferon
    Lesion
    Magnetic Resonance Imaging (MRI)
    Plaque
    Randomised
    Relapse
    Relapsing/remitting MS
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