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  Extracorporeal photochemotherapy: a safety and tolerability pilot study with preliminary efficacy results in refractory relapsing-remitting multiple sclerosis.

summary: Extracorporeal photochemotherapy (ECP) is an immunomodulating procedure consisting of autologous reinfusion of peripheral blood mononuclear cells after direct exposure to 8-methoxy-psoralen and UV-A. This study confirms ECP safety and tolerability and suggests that this treatment might be useful as a therapeutic alternative in the subgroup of relapsing-remitting MS patients not responsive to or not eligible for traditional immunomodulating or immunosuppressive treatments.

authors: Cavaletti G, Perseghin P, Dassi M, Cavarretta R, Frigo M, Caputo D, Stanzani L, Tagliabue E, Zoia C, Grimaldi M, Isella V, Rota S, Ferrarese C, Frattola L.

source: Neurol Sci. 2006 Apr;27(1):24-32.

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category: Clinical Trials and Therapeutics

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glossary:

    Cell
    Immunoglobulin
    Immunosuppressio
    Multiple sclerosis
    Peripheral
    Relapsing/remitting MS
    Ribonucleic acid
    Sclerosis
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