summary: Fatigue can be a major problem in people with MS. Its cause and mechanisms are still unknown. In this study the authors aimed to investigate whether this fatigue could be caused by a dysfunction in some of the parts of the central nervous system in charge of sending the signal for the muscles being able to move. They finally concluded that some degree of this specific part of the central nervous system could be involved in fatigue in MS.

authors: Andreasen A, Jakobsen J, Petersen T, Andersen H

source: Mult Scler. 2009 May 22

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