summary: The role of genes in the pathogenesis of MS is complex. The authors found an association between a gene and the severity of MS, in terms of symptoms, brain lesions and molecular MRI measures in the brain, suggesting that it may be involved.

authors: Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini SE, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P, Lincoln R, Gomez R, Caillier S, George M, Wang J, Nelson SJ, Cree BA, Hauser SL, Pelletier D

source: Brain. 2008 Nov 20. [Epub ahead of print]

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