summary: In this magnetic resonance imaging study, the authors assessed the volume of the hippocampus, a brain area that is specifically involved in memory function, in people with relapsing-remitting and primary-progressive MS, comparing them with healthy controls, and looked at clinical association with memory dysfunction. They found that the volume of the hippocampus was reduced in people with MS compared with controls, but the correlation between the volume loss in this specific area and the memory performance was rather weak. This suggests that there may be additional factors to hippocampal volume loss in contributing to memory dysfunction in MS.

authors: Anderson V, Fisniku L, Khaleeli Z, Summers M, Penny S, Altmann D, Thompson A, Ron M, Miller D.

source: Mult Scler. 2010 Jul 14. [Epub ahead of print]

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