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  Intrathecal IgM production at clinical onset correlates with a more severe disease course in multiple sclerosis

summary: This paper suggests that IgM levels in the spinal fluid of patients at the onset of MS symptoms may be a guide to their prognosis over the next 15 years.

authors: Perini P, Ranzato F, Calabrese M, Battistin L, Gallo P.

source: J Neurol Neurosurg Psychiatry. 2006 Aug;77(8):953-5. Epub 2006 Mar 30.

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category: Immunology

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