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  IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis

summary: This study helps to clarify the role of IL-23, a specific immunological molecule involved in the inflammatory response, in the pathogenesis of EAE, a mouse model of human multiple sclerosis.

authors: Thakker P, Leach MW, Kuang W, Benoit SE, Leonard JP, Marusic S.

source: J Immunol. 2007 Feb 15;178(4):2589-98.

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category: Immunology

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    Animal models
    Experimental
    Gene
    Immunoglobulin
    Immunosuppressio
    Molecule
    Multiple sclerosis
    Myelitis
    Sclerosis
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