summary: The presence of cortical lesions (CLs) and their topographic distribution in the brains of patients with multiple sclerosis (MS) have been clearly shown by recent histopathologic studies. The authors studied 149 people with MS (103 relapsing-remitting [RR] and 46 primary progressive [PP]) with an MRI examination, which included a specific sequence for CL assessment. They concluded that people with RRMS and PPMS share more similarities than differences in terms of CL number, volume, topographic distribution, and frequency.

authors: Calabrese M, Battaglini M, Giorgio A, Atzori M, Bernardi V, Mattisi I, Gallo P, De Stefano N.

source: Neurology. 2010 Aug 25. [Epub ahead of print]

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