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  Immunomodulator FTY720 Induces Myofibroblast Differentiation via the Lysophospholipid Receptor S1P3 and Smad3 Signaling

summary: This study clarifies the mechanism of action in myofibroblast differentiation of the new immunomodulator FTY720, recently introduced in MS therapy.

authors: Keller CD, Rivera Gil P, Tolle M, van der Giet M, Chun J, Radeke HH, Schafer-Korting M, Kleuser B.

source: Am J Pathol. 2007 Jan;170(1):281-92.

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category: Cell Biology

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    Fibroblast
    Immunoglobulin
    Immunosuppressio
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