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summary: In this study the investigators took blood from people at different stages of MS and looked at the immune profile of the dendritic cells, which are part of the body’s immunological response triggering system. They found differences in the expression of cell surface markers and cytokines in MS compared with controls and, interestingly, differences in secondary progressive MS compared with relapsing remitting MS.
authors: Karni A, Abraham M, Monsonego A, Cai G, Freeman GJ, Hafler D, Khoury SJ, Weiner HL.
source: J Immunol. 2006 Sep 15;177(6):4196-4202.
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category: Immunology
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glossary:
ACE
Cell
Cytokine
Dendritic cells
Immune response
Immunoglobulin
Immunosuppressio
Multiple sclerosis
Relapsing/remitting MS
Sclerosis
Secondary progressive multiple sclerosis
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