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  Integrating risk factors: HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis.

summary: This study focused on the relationship between two risk factors associated with the development of MS, namely antibodies against Epstein-Barr virus and a specific genetic pattern. The authors found that the level of antibody was an independent risk factor for MS even after accounting for any association with genetic pattern, but when the two factors occurred together, the risk of developing MS increased further.

authors: De Jager PL, Simon KC, Munger KL, Rioux JD, Hafler DA, Ascherio A.

source: Neurology. 2008 Mar 25;70(13 Pt 2):1113-8. Epub 2008 Feb 13

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category: Immunology

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glossary:

    Antibodies
    Antigen
    Gene
    Genetic
    Multiple sclerosis
    Sclerosis
    Virus
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