summary: People with MS may occasionally develop some degree of cognitive dysfunction, although the mechanisms by which this dysfunction appears are not yet fully understood. This study shows that intellectual enrichment protects against cognitive decline secondarily to MS, supporting the cognitive reserve hypothesis, which says that lifetime intellectual enrichment lessens the negative impact of brain disease on cognition.

authors: Sumowski JF, Wylie GR, Deluca J, Chiaravalloti N.

source: Brain. 2009 Dec 28

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