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summary: This study investigated the role of Intravenous immunoglobulin (IVIG) in reducing relapses in RRMS, using a rat model of MS. It was found that IVIG can only cross the blood brain barrier into the CSF (fluid around the brain) in areas where the barrier is damaged by inflammation.
authors: Jorgensen SH, Storm N, Jensen PE, Laursen H, Sorensen PS.
source: Exp Brain Res. 2006 Nov 8; [Epub ahead of print]
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category: Clinical Trials and Therapeutics
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glossary:
Brain
Central nervous system
Cerebrospinal fluid (CSF)
Experimental
Immunoglobulin
Immunosuppressio
Inflammation
Intravenous
Lesion
Myelitis
Nervous system
Plaque
Relapse
Relapsing/remitting MS
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