summary: MS is an inflammatory-demyelinating disease of the central nervous system. Although in primary progressive MS (PPMS), a form of MS characterised by clinical deterioration from the start, inflammation is considered to be less frequent than in other forms of MS, some acute inflammatory lesions in the brain and the spinal cord can be seen. In this longitudinal study carried out with people with PPMS, the authors found that a third of the participants experienced an early inflammatory phase, which seemed to have some impact on subsequent accrual of disability.

authors: Khaleeli Z, Ciccarelli O, Mizskiel K, Altmann D, Miller D, Thompson A

source: Mult Scler. 2010 Mar;16(3):317-24

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