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summary: MS is an inflammatory-demyelinating disease of the central nervous system and studies suggest that the cerebellar cortex is a major site of demyelination. In this study, the authors investigated the involvement of the cerebellar cortex in MS and found that it is severely affected at an early stage in people with MS. Also, they suggest that monitoring of both volume and lesions in the cerebellar cortex may be of great help in understanding the mechanisms underlying disease progression.
authors: Calabrese M, Mattisi I, Favaretto A, Rinaldi F, Atzori M, Bernardi V, Barachino L, Romualdi C, Rinaldi L, Perini P, Gallo P
source: J Neurol Neurosurg Psychiatry. 2009 Dec 3
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category: Imaging
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glossary:
Central nervous system
Cortex
Demyelination
Lesion
Magnetic
Multiple sclerosis
Myelin
Nervous system
Plaque
Sclerosis
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