summary: It is known that the damage which occurs in the axons (specific parts of the neurons in charge of the conduction of electrical signal) is, at least partly, responsible for the development of disability in MS. It is also known that acute inflammation is involved in causing axonal damage. The authors of this study have validated the usefulness of a specific MRI technique (MTR) in monitoring the processes of damage (demyelination) and recovery (remyelination) which take place when an acute MS lesion appears, considering that the better the recovery the lower the probability of axonal damage.

authors: Giacomini PS, Levesque IR, Ribeiro L, Narayanan S, Francis SJ, Pike GB, Arnold DL

source: Arch Neurol. 2009 Mar;66(3):375-81

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