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summary: In this study of 50 patients with severe RRMS treated with mitoxantrone, one third of patients continued to progress during treatment, although during the follow-up period this number decreased. The patients progressed despite there being no active lesions on their MRI scans. Ten per cent of patients withdrew from treatment due to side effects.
authors: Buttinelli C, Clemenzi A, Borriello G, Denaro F, Pozzilli C, Fieschi C.
source: Eur J Neurol. 2007 Nov;14(11):1281-1287.Links
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category: Clinical Trials and Therapeutics
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glossary:
Computerized
Lesion
Magnetic Resonance Imaging (MRI)
Multiple sclerosis
Plaque
Relapsing/remitting MS
Sclerosis
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