summary: The corpus callosum is one of the most important white matter tracts in the brain and forms the major connection between the two cerebral hemispheres, being involved in the performance of complex tasks. The corpus callosum is one of the regions of the brain affected in MS, but its study by conventional MRI techniques has not been satisfactory. The authors found that abnormalities in the corpus callosum can be assessed with new quantitative MRI techniques and are associated with cognitive and complex upper-extremity dysfunction in MS.

authors: Ozturk A, Smith S, Gordon-Lipkin E, Harrison D, Shiee N, Pham D, Caffo B, Calabresi P, Reich D

source: Mult Scler. 2010 Feb;16(2):166-77

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