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summary: The authors looked for N-acetylaspartic acid, a neuron specific marker, in the cerebrospinal fluid of people with different subtypes of MS. They found correlations with clinical disability and with imaging measures of lesion load. They concluded that it is therefore an important marker of disease severity.
authors: Jasperse B, Jakobs C, Eikelenboom MJ, Dijkstra CD, Uitdehaag BM, Barkhof F, Polman CH, Teunissen CE.
source: J Neurol. 2007 Apr 6
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category: Diagnosis
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glossary:
ACE
Cerebrospinal fluid (CSF)
Disability
Lesion
Multiple sclerosis
Neuron
Plaque
Sclerosis
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