summary: The prognosis of MS may vary amongst people and as yet there are no significant markers which can predict a less favourable clinical evolution. The authors have found that, in people with relapsing-remitting MS (RRMS), higher levels of a protein called ‘neurofilament light’ (which supplies structural strength to neurons) in their cerebrospinal fluid were associated with a worse long-term prognosis. The authors suggest that elevated levels of neurofilament light could be used as a prognostic marker in early RRMS.

authors: Salzer J, Svenningsson A, Sundström P

source: Mult Scler. 2010 Jan 19

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