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  Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis.

summary: In this paper the authors suggest that a defect of Voltage-gated sodium channels aggregation might be involved in the remyelination failure in demyelinated lesions with spared axons and oligodendroglial cells.

authors: Coman I, Aigrot MS, Seilhean D, Reynolds R, Girault JA, Zalc B, Lubetzki C.

source: Brain. 2006 Jun 9; [Epub ahead of print]

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category: Pathology

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glossary:

    Axon
    Cell
    Demyelination
    Glial cells
    Lesion
    Multiple sclerosis
    Myelin
    Plaque
    Proteins
    Remyelination
    Sclerosis
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