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summary: This rat study investigated the effect of interferon on oligodendrocytes, the remyelinating cells of the central nervous system. They found only an indirect effect of interferon on differentiation of oligodendrocytes from their precursors in the presence of other cells, astrocytes and microglia, which needs to be clarified with human studies.
authors: Heine S, Ebnet J, Maysami S, Stangel M.
source: J Neuroimmunol. 2006 Jun 2; [Epub ahead of print]
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category: Immunology
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glossary:
Astrocyte
Cell
Central nervous system
Glial cells
Interferon
Microglia
Myelin
Nervous system
Oligodendrocyte
Oligodendrocyte
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