summary: It is known that MS more frequently affects women than men. It is also known that relapses occur less frequently during pregnancy, and that there is a rebound effect with an increase in relapse frequency after delivery. All these facts indicate a hormonal involvement in the pathogenesis of the disease, especially in the appearance of relapses. The authors of this study aimed to investigate the influence of the number of births in the risk of development of secondary progression. They found no evidence that parity (the number of times a woman has given birth) could influence the risk of such progression after the relapsing-remitting phase.

authors: Koch M, Uyttenboogaart M, Heersema D, Steen C, De Keyser J

source: J Neurol Neurosurg Psychiatry. 2009 Jun;80(6):676-8

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category: Epidemiology

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